@Aron. I would say that it can be quite addictive, as this is a diluted form of how The Queen is controlling Mouthpiece, and he's completely devoted.
Long term effects would impair the ability to think for one's self, and cause a sort of disconnect with your identity.
The immediate effects include elation, drowsiness, and pain reduction
Side effects include lethargy, confusion, and nausea
Some users may have a genetic resistance to Bug Juice (this is also found in some Myrmidons, leading to disobedience of The Queen) which may trigger violent side effects like vomiting, trouble breathing, and chest pain.
It's usually used as a pain reliever, recreational drug, or sleep inducer.
Bug Juice, in essence, is essentially The Queen's pheromones altered to be compatible with humanoids. Since The Queen can alter her pheromones to influence the state of the hive, it could be possible to potentially figure out how this happens and remove narcotic effects.
I wouldn't say there's anything necessarily inhumane about the production of Bug Juice, but some may object because of it's Myrmidon origins, or may be grossed out that it's excreted from The Queen.